Case Study | Accelerating Enrollment for a Late-Stage Observational Study

Client: Leading Precision Diagnostics Biotech
Study: Large-Scale Observational Research Study 

Challenge

A leading precision diagnostics biotech company was nearing the close-out phase of a large observational study and needed to rapidly complete patient enrollment without adding operational burden to internal teams.

Key requirements included:

• Rapid stand-up of compliant workflows

• Coordination with external mobile phlebotomy partners

• High-volume chart review and patient outreach

• Predictable, audit-ready execution under tight timelines

Solution

The biotech partner engaged Aton Health to design, operationalize, and execute an end-to-end enrollment acceleration program using Aton’s TrialSight™ platform and coordinated clinical operations.

Key elements of Aton Health’s approach included:

• Rapid contract execution with a national mobile phlebotomy vendor

• Custom internal process flows aligned to study protocols

• Full study build within Aton’s TrialSight™ platform

• Internal team training prior to Site Initiation Visit (SIV)

• Pre-launch testing to ensure operational readiness

• High-throughput chart review and patient outreach

Aton Health moved from initial engagement to first patient enrolled in under 90 days, while maintaining regulatory rigor and data quality throughout the process.

Impact

In a highly compressed execution window, Aton Health delivered measurable results:

• 5,037 patient charts reviewed

• 1,071 patient outreach contacts completed

• 10 unique study coordinators deployed

• 14 analysts supporting screening and outreach

• First patient enrolled within one week of launch

• 185 patients consented

Aton Health successfully enabled rapid close-out enrollment efficiently, predictably, and at scale.

Timeline Highlights

• Oct 1, 2025: Verbal commitment from biotech partner

• Oct 20–23: Vendor contract signed; internal workflows completed

• Nov 17: TrialSight™ study build initiated

• Nov 20: SIV completed and Master Services Agreement signed

• Dec 8: IRB approval received

• Dec 15: First patient enrolled

• Dec 31: 185th patient consented

The Aton Health Advantage

This engagement demonstrates Aton Health’s ability to:

• Stand up complex observational studies rapidly

• Integrate technology, clinical operations, and vendor coordination

• Drive real enrollment outcomes under intense time pressure

• Act as a trusted execution partner, not just a platform provider